Generic name:cerliponase alfa [ ser-LIP-oh-nase-AL-fa ]
Drug class:Lysosomal enzymes
What is Brineura?
Brineura is used to slow the loss of ability to crawl or walk in children with symptoms of a rare genetic condition called ceroid lipofuscinosis type 2 disease (CLN2). Brineura is for use in children who are at least 3 years old.
Brineura may help slow the loss of certain physical abilities in children with ceroid lipofuscinosis type 2 disease (CLN2). However, this medicine is not a cure for this condition.
Brineura may also be used for purposes not listed in this medication guide.
Warnings
Get emergency medical help if your child has signs of an allergic reaction within 24 hours after each infusion. Symptoms may include fever, vomiting, fussiness, hives, difficult breathing, and swelling in the face or throat.
Before taking this medicine
Your child should not be treated with Brineura if he or she is allergic to it, or if the child has:
complications with the surgically implanted catheter used to deliver Brineura;
any sign of infection on the child's scalp in the area around the implanted catheter; or
a shunt in the brain (to help drain fluid build-up around the brain).
Tell your doctor if your child has ever had:
slow heartbeats;
a heart defect; or
heart rhythm problems.
Brineura is not approved for use by anyone younger than 3 years old.
