Brinzolamide Eye Drops

Dosage form: ophthalmic suspension
Drug class:Ophthalmic glaucoma agents

Medically reviewed by Drugs.com. Last updated on Apr 1, 2022.

Indications and Usage for Brinzolamide Eye Drops

Brinzolamide ophthalmic suspension is a carbonic anhydrase inhibitor indicated in the treatment of elevated intraocular pressure (IOP) in patients with ocular hypertension or open-angle glaucoma.

Brinzolamide Eye Drops Dosage and Administration

The recommended dose is one drop of brinzolamide ophthalmic suspension in the affected eye(s) 3 times daily. Brinzolamide ophthalmic suspension may be used concomitantly with other topical ophthalmic drug products to lower IOP. If more than one topical ophthalmic drug is being used, the drugs should be administered at least 10 minutes apart.

Dosage Forms and Strengths

Ophthalmic suspension containing brinzolamide 10 mg/mL (1%).

Contraindications

Brinzolamide ophthalmic suspension is contraindicated in patients who are hypersensitive to any component of this product.

Warnings and Precautions

Sulfonamide Hypersensitivity Reactions

Brinzolamide ophthalmic suspension is a sulfonamide and although administered topically, it is absorbed systemically. Therefore, the same types of adverse reactions that are attributable to sulfonamides may occur with topical administration of brinzolamide ophthalmic suspension. Fatalities have occurred, although rarely, due to severe reactions to sulfonamides, including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, and other blood dyscrasias. Sensitization may recur when a sulfonamide is readministered irrespective of the route of administration. If signs of serious reactions or hy...