Brodalumab
Generic name: brodalumab [ broe-DAL-ue-mab ]
Brand name: Siliq
Dosage form: subcutaneous solution (210 mg/1.5 mL)
Drug class:Interleukin inhibitors
What is brodalumab?
Brodalumab is used to treat moderate to severe plaque psoriasis in adults.
Brodalumab is usually given after other treatments have failed.
Brodalumab is available only under a special program. You must be registered in the program and understand the risks and benefits of brodalumab.
Brodalumab may also be used for purposes not listed in this medication guide.
Warnings
Some people have thoughts about suicide while taking this medicine. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor, such as mood changes, anxiety, or depression.
Brodalumab affects your immune system. You may get infections more easily. Call your doctor if you have symptoms such as fever, chills, cough, skin sores, diarrhea, stomach cramps, or burning urination.
Before taking this medicine
You should not use brodalumab if you have Crohn's disease.
Tell your doctor if you have ever had:
an active or chronic infection;
tuberculosis; or
anxiety, depression, mental illness, or a mood disorder.
Tell your doctor if you have ever had tuberculosis or if anyone in your household has tuberculosis. Also tell your doctor if you have recently traveled. Tuberculosis is more common in certain parts of the world, and you may have been exposed during travel.
Tell your doctor if you are pregnant or breastfeeding.
Brodalumab is not approved for use by anyone younger than 18 years old.
How is brodalumab given?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Brodalumab is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.
Brodalumab is usually given once a week for 3 weeks, and then once every 2 weeks thereafter. Follow your doctor's dosing instructions.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions.
Prepare an injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.
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