Brodalumab (Subcutaneous)
Medically reviewed by Drugs.com. Last updated on Mar 22, 2022.
Suicidal ideation and behavior, including completed suicides, have occurred with brodalumab. Weigh potential risks and benefits in each patient prior to initiation, and advise patients and caregivers to seek medical attention for new or worsening depression, anxiety, or other mood changes. Refer patients with new or worsening suicidal ideation and behavior to a mental health professional. Brodalumab is only available through a restricted program called the Siliq REMS Program .
Commonly used brand name(s)
In the U.S.
- Siliq
Available Dosage Forms:
- Solution
Therapeutic Class: Antipsoriatic
Pharmacologic Class: Monoclonal Antibody
Uses for brodalumab
Brodalumab injection is used to treat moderate to severe plaque psoriasis in patients who may benefit from receiving phototherapy (ultraviolet light treatment) or other treatments. Plaque psoriasis is a skin disease with red patches and white scales that don't go away.
Brodalumab is only available through a restricted access program. Doctors who are enrolled in the restricted program can write a prescription for brodalumab.
Before using brodalumab
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For brodalumab, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to brodalumab or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of brodalumab injection in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of brodalumab injection in the elderly.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking brodalumab, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using brodalumab with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
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