Cabozantinib
Generic name: cabozantinib [ KA-boe-ZAN-ti-nib ]
Brand names: Cabometyx, Cometriq
Dosage forms: oral capsule (100 mg daily-dose; 140 mg daily-dose; 60 mg daily-dose); oral tablet (20 mg; 40 mg; 60 mg)
Drug classes:Multikinase inhibitors, VEGF/VEGFR inhibitors
What is cabozantinib?
Cabometyx is used to treat advanced kidney cancer, sometimes in combination with another medicine called nivolumab.
Cabometyx is also used to treat liver cancer in people who have been previously treated with sorafenib.
Cometriq is used to treat thyroid cancer that has spread to other parts of the body.
Cabozantinib may also be used for purposes not listed in this medication guide.
Warnings
Cabozantinib may cause a perforation (a hole or tear) or a fistula (an abnormal passageway) within your stomach or intestines. Cabozantinib can also increase your risk of serious bleeding.
Call your doctor if you have: severe stomach pain, choking or gagging when you eat or drink, unusual bleeding, bloody or tarry stools, heavy menstrual bleeding, or if you cough up blood.
Before taking this medicine
Tell your doctor if you have:
an open wound on your skin (or a wound that is still healing);
bleeding problems (such as bloody or tarry stools, or coughing up blood or vomit that looks like coffee grounds);
liver disease; or
a pre-existing dental problem.
You may need to have a negative pregnancy test before starting this treatment.
Cabozantinib may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using cabozantinib and for at least 4 months after your last dose. Tell your doctor if you think you might be pregnant.
This medicine may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because cabozantinib can harm an unborn baby.
You should not breastfeed while using this medicine, and for at least 4 months after your last dose.
How should I take cabozantinib?
Follow all directions on your...
