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Calaspargase pegol
  • Treatments
  • Acute Lymphoblastic Leukemia

Calaspargase pegol

Generic name: calaspargase pegol [ kal-AS-par-jase-PEG-ol ]
Brand name: Asparlas
Dosage form: intravenous solution (mknl 750 units/mL)
Drug class:Miscellaneous antineoplastics

Medically reviewed by Drugs.com on Oct 19, 2021. Written by Cerner Multum.

What is calaspargase pegol?

Calaspargase pegol is used to treat acute lymphoblastic leukemia in children and young adults from 1 month to 21 years old.

Calaspargase pegol may also be used for purposes not listed in this medication guide.

Warnings

You should not use calaspargase pegol if you have ever received pegaspargase and it caused an allergic reaction, a blood clot, pancreatitis, bleeding, or liver problems.

Before taking this medicine

You should not use calaspargase pegol if you are allergic to it, or if:

  • you have liver disease;

  • you have had a serious allergic reaction to pegaspargase; or

  • you have had a blood clot, pancreatitis, or serious bleeding caused by using asparaginase.

Tell your doctor if you have ever had:

  • pancreatitis;

  • heart problems;

  • a blood clot; or

  • liver disease.

Calaspargase pegol may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 3 months after your last dose.

Calaspargase pegol may interact with birth control pills. To prevent pregnancy while using calaspargase pegol, use an effective non-oral form of birth control (injection, implant, skin patch, vaginal ring) plus a barrier form of birth control (condom, diaphragm, cervical cap, contraceptive sponge).

Do not breastfeed while using this medicine, and for at least 3 months after your last dose.

How should I take calaspargase pegol?

Calaspargase pegol is given as an infusion into a vein. A healthcare provider will give you this injection.

Calaspargase pegol is usually given once every 21 days. Your doctor will determine how long to treat you with calaspargase pegol.

Calaspargase pegol doses are based on body surface area (height and weight). Your dose needs may change if you gain or lose weight or if you are still growing.

You will need frequent medical tests.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your calaspargase pegol injection.

What happens if I overdose?

Seek emer...