Calaspargase pegol-mknl (Intravenous)
Medically reviewed by Drugs.com. Last updated on May 4, 2022.
Commonly used brand name(s)
In the U.S.
- Asparlas
Available Dosage Forms:
- Solution
Therapeutic Class: Antineoplastic Agent
Pharmacologic Class: Calaspargase Pegol
Uses for calaspargase pegol-mknl
Calaspargase pegol-mknl injection is used together with other cancer medicines to treat patients with acute lymphoblastic leukemia (ALL), a type of white blood cell cancer.
Calaspargase pegol-mknl is to be given only by or under the direct supervision of your doctor.
Before using calaspargase pegol-mknl
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For calaspargase pegol-mknl, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to calaspargase pegol-mknl or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of calaspargase pegol-mknl injection in children 1 month to 16 years of age. Safety and efficacy have been established.
Geriatric
No information is available on the relationship of age to the effects of calaspargase pegol-mknl injection in geriatric patients.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of calaspargase pegol-mknl. Make sure you tell your doctor if you have any other medical problems, especially:
- Bleeding problems (eg, coagulopathy), severe or symptomatic or
- Blood clotting problems or
- Liver disease or
- Pancreatitis—Use with caution. May make these conditions worse.
- Blood clots, bleeding problems, or pancreatitis (swelling of the pancreas), serious, history of during previous treatment with calaspargase pegol-mknl or similar medicines or
- Liver disease, severe—Should not be used in patients with these conditions.
