Captracin Patch

Generic name: menthol and capsaicin
Dosage form: patch
Drug class:Topical rubefacient

Medically reviewed by Drugs.com. Last updated on Nov 22, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Captracin Patch Description

Captracin Patch contains capsaicin and menthol in a localized dermal delivery system. The capsaicin in Captracin is a synthetic equivalent of the naturally occurring compound found in chili peppers. Capsaicin is soluble in alcohol, acetone, and ethyl acetate and very slightly soluble in water. The menthol is slightly soluble in water.

Captracin is a single-use patch stored in a foil pouch. Each Captracin Patch is 7.6 cm x 12.7 cm (97 cm²) and consists of a polyester backing film coated with a drug-containing silicone adhesive mixture, and covered with a removable polyester release liner.

The empirical formula for capsaicin is C H NO , with a molecular weight of 305.42. The chemical compound capsaicin [(E)-8-methyl-N-vanillyl-6-nonenamide] is an activating ligand for transient receptor potential vanilloid 1 receptor (TRPV1) and it has the following structure:

The empirical formula for menthol is C H O, with a molecular weight of 156.27. The chemical compound menthol [(1R,2S,5R)-2-isopropyl-5-methylcyclohexanol ] is an activating ligand for transient receptor potential cation channel subfamily M member 8 (TRPM8). It has the following structure:

Each Captracin Patch contains 0.0375% capsaicin (0.0375 grams of capsaicin per patch) and 5.00% menthol (5 grams of menthol per patch). The Captracin Patch contains the following inactive ingredients: Non-Toxic Acrylic.

Indications and Usage for Captracin Patch

Captracin Patch is indicated for the temporary relief of minor aches and muscle pains associated with arthritis, simple backache, strains, muscle soreness and stiffness.

Captracin Patch is an external analgesic/counterirritant.

Contraindications

Captracin Patch is contraindicated for those patients with a history of hypersensitivity to any of the components of the preparation.

Warnings

• For external use only.
• Use only a...