Cardene Injection
Generic name:nicardipine hydrochloride
Dosage form: injection, solution
Drug class:Calcium channel blocking agents
Medically reviewed by Drugs.com. Last updated on Mar 1, 2022.
On This Page
- Indications and Usage
- Dosage and Administration
- Dosage Forms and Strengths
- Contraindications
- Warnings and Precautions
- Adverse Reactions/Side Effects
- Drug Interactions
- Use In Specific Populations
- Overdosage
- Description
- Clinical Pharmacology
- Nonclinical Toxicology
- Clinical Studies
- How Supplied/Storage and Handling
Indications and Usage for Cardene Injection
Hypertension
CARDENE® I.V. (nicardipine hydrochloride) is indicated for the short-term treatment of hypertension when oral therapy is not feasible or not desirable. For prolonged control of blood pressure, transfer patients to oral medication as soon as their clinical condition permits [see Dosage and Administration (2.1)].
Cardene Injection Dosage and Administration
Recommended Dosing
CARDENE I.V. is intended for intravenous use. Titrate dose to achieve the desired blood pressure reduction. Individualize dosage depending on the blood pressure to be obtained and the response of the patient.
Dosage as a Substitute for Oral Nicardipine Therapy
The intravenous infusion rate required to produce an average plasma concentration equivalent to a given oral dose at steady state is shown in the following table:
Oral CARDENE Dose | Equivalent I.V. Infusion Rate 20 mg in 200 mL | Equivalent I.V. Infusion Rate 40 mg in 200 mL |