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Cardene Injection
  • Professionals
  • FDA PI

Cardene Injection

Generic name:nicardipine hydrochloride
Dosage form: injection, solution
Drug class:Calcium channel blocking agents

Medically reviewed by Drugs.com. Last updated on Mar 1, 2022.

Indications and Usage for Cardene Injection

Hypertension

CARDENE® I.V. (nicardipine hydrochloride) is indicated for the short-term treatment of hypertension when oral therapy is not feasible or not desirable. For prolonged control of blood pressure, transfer patients to oral medication as soon as their clinical condition permits [see Dosage and Administration (2.1)].

Cardene Injection Dosage and Administration

Recommended Dosing

CARDENE I.V. is intended for intravenous use. Titrate dose to achieve the desired blood pressure reduction. Individualize dosage depending on the blood pressure to be obtained and the response of the patient.

Dosage as a Substitute for Oral Nicardipine Therapy

The intravenous infusion rate required to produce an average plasma concentration equivalent to a given oral dose at steady state is shown in the following table:

Oral CARDENE Dose

Equivalent I.V. Infusion Rate

20 mg in 200 mL
(0.1 mg/mL)

Equivalent I.V. Infusion Rate

40 mg in 200 mL
(0.2 mg/mL)

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