Medically reviewed by Drugs.com. Last updated on Apr 26, 2022.
Commonly used brand name(s)
In the U.S.
- Kyprolis
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Antineoplastic Agent
Pharmacologic Class: Proteasome Inhibitor
Uses for carfilzomib
Carfilzomib injection is used alone to treat relapsed (cancer that has come back) or refractory (cancer that did not respond to treatment) multiple myeloma (a type of bone marrow cancer) in patients who have received 1 or more previous treatments.
Carfilzomib injection is also used together with other medicines (eg, dexamethasone, daratumumab and dexamethasone, lenalidomide and dexamethasone, and daratumumab and hyaluronidase-fihj and dexamethasone) to treat relapsed or refractory multiple myeloma in patients who have received 1 to 3 previous treatments.
Carfilzomib is an antineoplastic agent (cancer medicine). It interferes with the growth of cancer cells, which are eventually destroyed by the body.
Carfilzomib is to be given only by or under the supervision of your doctor.
Before using carfilzomib
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For carfilzomib, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to carfilzomib or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of carfilzomib injection in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of carfilzomib injection in the elderly. However, elderly patients are more likely to have heart problems, which may require caution and an adjustment in the dose for patients receiving carfilzo...
