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Cetuximab
  • Treatments
  • Colorectal Cancer

Cetuximab

Generic name: cetuximab [ se-TUX-i-mab ]
Brand name: Erbitux
Dosage form: intravenous solution (2 mg/mL)
Drug class:EGFR inhibitors

Medically reviewed by Drugs.com on Feb 3, 2021. Written by Cerner Multum.

What is cetuximab?

Cetuximab is used to treat cancers of the colon and rectum. It is also used to treat head and neck cancer.

Cetuximab may also be used for purposes not listed in this medication guide.

Warnings

Cetuximab has caused life-threatening side effects in a small number of patients. Your caregivers will watch you closely after you receive each dose of cetuximab.

Side effects may occur when this medicine is injected into your vein. Tell your caregiver right away if you feel dizzy, feverish, itchy, or short of breath during the infusion.

Cetuximab can have long-lasting effects on your body. You may need frequent medical tests for at least 8 weeks after your last dose.

Before taking this medicine

You should not use this medicine if you are allergic to cetuximab or to mouse protein.

Tell your doctor if you have ever had:

  • heart rhythm problems;

  • lung disease or a breathing disorder;

  • congestive heart failure;

  • coronary artery disease (clogged arteries); or

  • an electrolyte imbalance (such as low levels of potassium or magnesium in your blood).

Tell your doctor if you are allergic to red meat, or if you've ever been bitten by a tick. If so, you may be more likely to have certain reactions during or shortly after injection of this medicine.

Cetuximab may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 2 months after your last dose. Tell your doctor if you become pregnant.

Do not breastfeed while using this medicine, and for at least 2 months after your last dose.

How is cetuximab given?

Cetuximab is given as an infusion into a vein. A healthcare provider will give you this injection.

cetuximab must be given slowly, and the infusion can take up to 2 hours to complete. You may be given other medications to help prevent serious side effects or allergic reaction.

Cetuximab is often used in combination with other cancer medications and/or radiation treatments. You may receive another cancer medicine 1 hour after your cetuximab infusion.

Cetuximab has caused life-threatening side effects in a small number of patients. After each cetuximab infusion, your caregivers will watch you closely to make sure you do not have any serious side effects.

Cetuximab is usually given until your ...