Generic name:aprepitant (intravenous route) [ ap-RE-pi-tant ]
Drug class:NK1 receptor antagonists
Medically reviewed by Drugs.com. Last updated on Apr 19, 2022.
Commonly used brand name(s)
In the U.S.
- Cinvanti
Available Dosage Forms:
- Emulsion
Therapeutic Class: Antiemetic
Pharmacologic Class: Neurokinin-1 Receptor Antagonist
Uses for Cinvanti
Aprepitant injection is used together with other medicines (eg, dexamethasone, granisetron, ondansetron) to prevent acute and delayed nausea and vomiting caused by cancer medicines (chemotherapy). It is a substance P/neurokinin 1 (NK1) receptor antagonist that works by blocking the signals to the brain that cause nausea and vomiting.
This medicine is given only by or under the direct supervision of your doctor.
Before using Cinvanti
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of aprepitant injection in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of aprepitant injection in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.
Breastfeeding
There are no adequate studies in women f...
