Ado-trastuzumab emtansine
Generic name: ado-trastuzumab emtansine [ AY-doe-tras-TOOZ-ue-mab-em-TAN-seen ]
Brand name: Kadcyla
Dosage form: intravenous powder for injection (100 mg; 160 mg)
Drug class:HER2 inhibitors
What is ado-trastuzumab emtansine?
Ado-trastuzumab emtansine is used to treat a HER2-positive breast cancer. ado-trastuzumab emtansine is used both for early breast cancer and for breast cancer that has spread to other parts of the body (metastatic).
Ado-trastuzumab emtansine is usually given after other treatments have failed.
Kadcyla (ado-trastuzumab) should not be used in place of Herceptin (trastuzumab).
Ado-trastuzumab emtansine may also be used for purposes not listed in this medication guide.
Warnings
Do not use if you are pregnant. Use effective birth control, and tell your doctor if you become pregnant during treatment.
This medicine can cause serious side effects on your liver or heart. Call your doctor at once if you have upper stomach pain, loss of appetite, dark urine, yellowing of your skin or eyes, shortness of breath, cough, swelling, rapid weight gain, fast or pounding heartbeats, dizziness, or if you feel like you might pass out.
Before taking this medicine
Tell your doctor if you have ever had:
heart problems;
liver disease (especially hepatitis B or C);
bleeding or blood clotting disorder such as hemophilia; or
asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorder.
You may need to have a negative pregnancy test before starting this treatment.
Ado-trastuzumab emtansine can harm an unborn baby if the mother or the father is using ado-trastuzumab emtansine.
If you are a woman, do not use ado-trastuzumab emtansine if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 7 months after your last dose.
If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 4 months after your last dose.
Tell your doctor right away if a pregnancy occurs while e...
