Adrucil (injection)
Generic name:fluorouracil (injection) [ FLOOR-oh-URE-a-sil ]
Drug class:Antimetabolites
The Adrucil brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
What is Adrucil?
Adrucil is used to treat cancer of the colon, rectum, breast, stomach, or pancreas.
Adrucil is often given in combination chemotherapy with other cancer drugs.
Adrucil may also be used for purposes not listed in this medication guide.
Warnings
Before using Adrucil tell your doctor about all your medical conditions or allergies, all medicines you use, and if you are pregnant or breastfeeding.
Before taking this medicine
Tell your doctor if you have ever had:
a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency;
heart problems; or
bone marrow depression.
Both men and women using Adrucil should use effective birth control to prevent pregnancy. Adrucil can harm an unborn baby if the mother or father is using this medicine.
Keep using birth control for at least 3 months after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using Adrucil.
This medicine may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because Adrucil can harm an unborn baby.
You should not breastfeed while using this medicine.
How is Adrucil given?
Adrucil is given as an infusion into a vein. A healthcare provider will give you this injection.
You may receive your first dose in a hospital or clinic setting to quickly treat any serious side effects.
Adrucil is often given in a treatment cycle, and you may need to use the medicine only on certain days of each cycle. This medicine is sometimes given in a continuous infusion over 24 to 46 hours.
How often you need Adrucils will depend on many factors, including side effects and how your body responds to the medicine. Your doctor will determine how long to treat you with this medicine.
Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Adrucil is injected.
Adrucil can increase your risk of bleeding or infection. You will need frequent medical tests. Your cancer treatments may be delayed based on the results of these tests.
