Aducanumab
Generic name: aducanumab [ A-due-KAN-ue-mab ]
Brand name: Aduhelm
Dosage form: intravenous solution (avwa 100 mg/mL)
Drug class:Miscellaneous central nervous system agents
What is aducanumab?
Aducanumab is used to treat people with Alzheimer's disease.
Aducanumab may also be used for purposes not listed in this medication guide.
Warnings
Aducanumab can cause temporary swelling or bleeding in the brain that usually clears up with time. This may cause no symptoms but can be serious. Call your doctor if you have headaches, dizziness, nausea, confusion, or vision changes.
Before taking this medicine
Aducanumab can cause a condition called Amyloid Related Imaging Abnormalities or "ARIA."
ARIA is a temporary swelling or small spots of bleeding in the brain that usually clears up with time. Your doctor may perform an MRI of your brain before you receive aducanumab.
Tell your doctor if you are pregnant or breastfeeding.
How is aducanumab given?
Aducanumab is injected into a vein by a healthcare provider.
This medicine is injected slowly over 1 hour.
Aducanumab is usually given every 4 weeks, at least 21 days apart.
You will need occasional brain MRIs while receiving aducanumab.
What happens if I miss a dose?
Call your doctor for instructions if you miss a dose.
What happens if I overdose?
In a medical setting an overdose would be treated quickly.
What should I avoid while receiving aducanumab?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Aducanumab side effects
Get emergency medical help if you have signs of an allergic reaction:hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your care provider if you have a rash, trouble breathing, or swelling in your face.
Aducanumab can cause temporary swelling or bleeding in the brain. Call your doctor if you have:
Common side effects of aducanumab may include:
ARIA with symptoms, or with signs that appear on an MRI;
headache; or
falls.
This is not a complete list of side effects and others may occur. Call your doctor for medical advi...
