Cobicistat, darunavir, emtricitabine, and tenofovir

Generic name: cobicistat, darunavir, emtricitabine, and tenofovir [ koe-BIK-i-stat, dar-UE-na-vir, EM-trye-SYE-ta-been, and-ten-OF-oh-vir ]
Brand name: Symtuza
Dosage form: oral tablet (150 mg-800 mg-200 mg-10 mg)
Drug class:Antiviral combinations

Medically reviewed by Drugs.com on Sep 20, 2021. Written by Cerner Multum.

What is cobicistat, darunavir, emtricitabine, and tenofovir (Symtuza)?

Cobicistat, darunavir, emtricitabine, and tenofovir (Symtuza) is a combination medicine that is used to treat HIV (human immunodeficiency virus). HIV can cause acquired immunodeficiency syndrome (AIDS). cobicistat, darunavir, emtricitabine, and tenofovir is not a cure for HIV or AIDS.

Symtuza is for use in adults and children weighing at least 88 pounds (40 kilograms).

Symtuza is sometimes used in people who have never been treated with other HIV medications.

Symtuza is also used to replace other HIV medications in adults with suppressed viral loads. Your doctor will determine which medication is best for you.

Symtuza may also be used for purposes not listed in this medication guide.

Warnings

Tell your doctor about all your other medicines. Some drugs should not be used with Symtuza.

Call your doctor at once if you have signs of a serious side effect--upper stomach pain, loss of appetite, vomiting, dark urine, clay-colored stools, yellowing of your skin or eyes, fever, tiredness, eye redness, muscle or joint pain, skin sores, or a skin rash with blistering.

If you've had hepatitis B, it may come back or get worse after you stop using this medicine. You may need liver function tests for several months.

Before taking this medicine

Some drugs should not be used with Symtuza. Your treatment plan may change if you also use:

• alfuzosin;

• cisapride;

• colchicine (in people with liver or kidney disease);

• elbasvir and grazoprevir;

• lovastatin or simvastatin;

• pimozide, lurasidone;

• rifampin;

• sildenafil<...