Cocaine hydrochloride (Nasal)
Medically reviewed by Drugs.com. Last updated on Feb 24, 2022.
Warning: Abuse and DependenceCNS stimulants, including cocaine hydrochloride, have a high potential for abuse and dependence .
Commonly used brand name(s)
In the U.S.
- Numbrino
Available Dosage Forms:
- Solution
Therapeutic Class: Anesthetic, Local
Chemical Class: Cocaine
Uses for cocaine hydrochloride
Cocaine hydrochloride nasal solution is used to numb the mucous membrane inside the nose before a medical procedure or surgery. Cocaine hydrochloride is a local anesthetic.
Cocaine hydrochloride is to be given only by or under the direct supervision of your doctor.
Before using cocaine hydrochloride
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For cocaine hydrochloride, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to cocaine hydrochloride or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of cocaine hydrochloride nasal solution in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of cocaine hydrochloride nasal solution in the elderly. However, elderly patients are more likely to have high blood pressure, which may require caution in patients receiving cocaine hydrochloride.
Breastfeeding
Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using cocaine hydrochloride.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of cocaine hydrochloride. Make sure you tell your doctor if you have any other medical problems, especially:
- Damaged nasal mucosa—Do not use in patients with this condition.
- Heart attack, history of or
- Heart failure, history of or
- Heart or blood vessel disease, history of or
- Heart rhythm problems, history of or
- Hyperten..