Dacomitinib
Generic name: dacomitinib [ DAK-oh-MI-ti-nib ]
Brand name: Vizimpro
Dosage form: oral tablet (15 mg; 30 mg; 45 mg)
Drug classes:EGFR inhibitors, HER2 inhibitors
What is dacomitinib?
Dacomitinib is used to treat non-small cell lung cancer that has spread to other parts of the body.
Dacomitinib is given only if your tumor has a specific genetic marker (an abnormal "EGFR" gene).
Dacomitinib may also be used for purposes not listed in this medication guide.
Warnings
Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.
Before taking this medicine
Tell your doctor if you have ever had:
frequent diarrhea; or
breathing problems (other than lung cancer).
May harm an unborn baby. You may need a pregnancy test to make sure you are not pregnant. Use birth control while using dacomitinib and for at least 17 days after your last dose. Tell your doctor if you become pregnant.
Do not breastfeed while using dacomitinib, and for at least 17 days after your last dose.
How should I take dacomitinib?
Your doctor will make sure you have the correct tumor type to be treated with dacomitinib.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Take the medicine at the same time each day, with or without food.
Drink plenty of liquids while you are taking dacomitinib.
If you vomit shortly after taking dacomitinib, do not take another dose. Wait until your next scheduled dose time to take the medicine again.
Dacomitinib can cause severe diarrhea, which can be life-threatening if it leads to dehydration or infection.
If you have diarrhea while taking dacomitinib: Call your doctor right away. You may need to start taking anti-diarrhea medicine such as loperamide (Imodium) to quickly treat diarrhea.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Skip the missed dose and use your next dose at the regular time. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
