Dactinomycin Injection
Dosage form: injection, powder, lyophilized, for solution
Drug class:Antibiotics / antineoplastics
Medically reviewed by Drugs.com. Last updated on Nov 1, 2020.
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Indications and Usage for Dactinomycin Injection
Wilms Tumor
Dactinomycin for Injection is indicated for the treatment of adult and pediatric patients with Wilms tumor, as part of a multi-phase, combination chemotherapy regimen.
Rhabdomyosarcoma
Dactinomycin for Injection is indicated for the treatment of adult and pediatric patients with rhabdomyosarcoma, as part of a multi-phase, combination chemotherapy regimen.
Ewing Sarcoma
Dactinomycin for Injection is indicated for the treatment of adult and pediatric patients with Ewing sarcoma, as part of a multi-phase, combination chemotherapy regimen.
Metastatic Nonseminomatous Testicular Cancer
Dactinomycin for Injection is indicated for the treatment of adult and pediatric patients with metastatic, nonseminomatous testicular cancer, as part of a multi-phase, combination chemotherapy regimen.
Gestational Trophoblastic Neoplasia
Dactinomycin for Injection is indicated for the treatment of post-menarchal patients with gestational trophoblastic neoplasia, as a single agent or as part of a combination chemotherapy regimen.
Regional Perfusion in Locally Recurrent and Locoregional Solid Malignancies
Dactinomycin for Injection is indicated for the treatment of adult patients with locally recurrent or locoregional solid malignancies, as a component of palliative or adjunctive regional perfusion.
Dactinomycin Injection Dosage and Administration
Recommended Dosage for Wilms Tumor
The recommended dose of dactinomycin for injection, as part of a multi-agent combination chemotherapy regimen, is 45 mcg/kg intravenously once every 3 to 6 weeks for up to 26 weeks.
Recommended Dosage for Rhabdomyosarcoma
The recommended dose of dactinomycin for injection, as part of a multi-agent combination chemotherapy regimen, is 15 mcg/kg intravenously once daily for 5 days every 3 to...
