Daklinza

Generic name:daclatasvir [ dak-LAT-as-vir ]
Drug class:NS5A inhibitors

Medically reviewed by Philip Thornton, DipPharm. Last updated on May 11, 2022.

What is Daklinza?

Daklinza is an antiviral medicine that prevents hepatitis C virus (HCV) from multiplying in your body.

Daklinza is used in combination with other medications to treat chronic hepatitis C in adults.

Daklinza treats specific genotypes of hepatitis C, and only in certain people. Use only the medications prescribed for you. Do not share your medicine with other people.

Daklinza must be given in combination with other antiviral medications and should not be used alone. It is usually given with sofosbuvir, with or without ribavirin.

Daklinza is sometimes used in people who also have HIV. Daclatasvir is not a treatment for HIV or AIDS.

Warnings

If you've ever had hepatitis B, it may become active or get worse while using or after you stop using Daklinza. You may need frequent liver function tests for several months.

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

Daklinza is sometimes used in combination with other medication. Read the medication guide or patient instructions provided with each medication in your combination therapy. Do not change your doses or medication schedule without your doctor's advice.

Before taking this medicine

You should not use Daklinza if you are allergic to daclatasvir.

When taking Daklinza with other medicine: To make sure all medicines are safe for you, tell your doctor about all your medical conditions, and if you are pregnant or breastfeeding.

Many drugs can interact and cause dangerous effects. Some drugs should not be used together with daclatasvir. Your doctor may change your treatment plan if you also use:

• rifampin;

• St. John's wort; or

• seizure medicine - carbamazepine, phenytoin.

To make sure Daklinza is safe for you, tell your doctor if you have ever had:

• hepatitis B;

• liver problems other than hepatitis C;

• a liver transplant;

• diabetes;

• heart disease;

• if you have recently used a heart rhythm medicine called amiodarone; or

• if you use a blood thinner (warfarin, Coumadin, Jantoven) and you have routine "INR" or prothrombin time tests.

Daklinza is some...