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Dalfampridine
  • Treatments
  • Multiple Sclerosis

Dalfampridine

Generic name: dalfampridine [ dal-FAM-pri-deen ]
Brand name: Ampyra
Dosage form: oral tablet, extended release (10 mg)
Drug class:Miscellaneous central nervous system agents

Medically reviewed by Drugs.com on Sep 22, 2021. Written by Cerner Multum.

What is dalfampridine?

Dalfampridine is used to improve walking in patients with multiple sclerosis (MS).

Dalfampridine may also be used for purposes not listed in this medication guide.

Warnings

Dalfampridine can cause a seizure, even if you never had one before. Taking too much dalfampridine may increase your risk of seizure. Your risk may also be higher if you have kidney problems or are older than 50.

Your kidney function may need to be tested before you start taking dalfampridine.

Stop taking dalfampridine and call your doctor right away if you have a seizure.

Before taking this medicine

You should not use this medicine if you are allergic to dalfampridine or 4-aminopyridine, or if you have:

  • moderate to severe kidney disease; or

  • if you've ever had a seizure.

Dalfampridine can cause a seizure, even if you never had one before. Your risk may also be higher if you have kidney problems or are older than 50.

Tell your doctor if you have ever had:

  • kidney disease; or

  • if you also take a form of this medicine obtained from a compounding pharmacy (fampridine, or 4-aminopyridine).

Older adults may be more sensitive to the effects of this medication.

It is not known if dalfampridine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using this medicine.

Not approved for use by anyone younger than 18 years old.

How should I take dalfampridine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Taking too much dalfampridine may increase your risk of seizure. Space your doses 12 hours apart. Do not take more than 2 tablets in 24 hours.

You may take dalfampridine with or without food.

Swallow the tablet whole and do not crush, chew, or break it. Breaking the pill may cause too much of the drug to be released at one time which can increase your risk of a seizure.

Do not use a tablet that has been crushed or broken.

Store at room temperature away from moisture and heat. Do not use past the expiration date on the label.

What happens if I miss a dose?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

What happens if I overdose?

Seek...