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Dalfopristin and quinupristin
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Dalfopristin and quinupristin

Generic name: dalfopristin and quinupristin [ dal-FOE-pris-tin-and-kwi-NYOO-pris-tin ]
Brand name: Synercid
Dosage form: intravenous powder for injection (350 mg-150 mg)
Drug class:Streptogramins

Medically reviewed by Drugs.com on Nov 19, 2021. Written by Cerner Multum.

What is dalfopristin and quinupristin?

Dalfopristin and quinupristin is a combination antibiotic that fights severe or life-threatening infection caused by bacteria.

Dalfopristin and quinupristin is used to treat severe infections of the skin or other body systems.

Dalfopristin and quinupristin may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use dalfopristin and quinupristin if you are allergic to it.

To make sure dalfopristin and quinupristin is safe for you, tell your doctor if you have ever had:

  • an allergic reaction to any antibiotic;

  • liver disease; or

  • kidney disease.

It is not known whether dalfopristin and quinupristin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether dalfopristin and quinupristin passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

How is dalfopristin and quinupristin given?

Dalfopristin and quinupristin is injected into a vein through an IV, sometimes with an infusion pump or through a central IV or "PICC" line.

This medicine is most often given in a hospital setting. However, you may be shown how to use an IV at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of needles, IV tubing, and other items used.

Dalfopristin and quinupristin must be given slowly, and the infusion can take at least 1 hour to complete.

Call your doctor at once if you have problems with your IV, or if the medicine does not flow freely from the IV bag through the tubing.

Dalfopristin and quinupristin is usually given for at least 7 days. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Dalfopristin and quinupristin will not treat a

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