Dantrolene

Generic name: dantrolene (oral) [ DAN-troe-leen ]
Brand names: Dantrium, Revonto, Ryanodex, Dantrium Intravenous
Dosage forms: intravenous powder for injection (20 mg; 250 mg); oral capsule (100 mg; 25 mg; 50 mg)
Drug class:Skeletal muscle relaxants

Medically reviewed by Drugs.com on May 11, 2021. Written by Cerner Multum.

What is dantrolene?

Dantrolene is a muscle relaxer that is used to treat muscle spasticity (stiffness and spasms) caused by conditions such as a spinal cord injury, stroke, cerebral palsy, or multiple sclerosis.

Dantrolene is also used to treat or prevent muscle stiffness and spasms caused by malignant hyperthermia (a rapid rise in body temperature and severe muscle contractions) that can occur during surgery with certain types of anesthesia.

Dantrolene may also be used for purposes not listed in this medication guide.

Warnings

You should not take dantrolene if you have active liver disease. Do not take dantrolene at a time when you need muscle tone for safe balance and movement during certain activities.

Dantrolene can cause life-threatening liver damage, especially if you take high doses. Do not take dantrolene in larger amounts or for longer than recommended.

Call your doctor right away if you have signs of liver problems such as nausea, upper stomach pain, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).

Before taking this medicine

You should not use d...