DermacinRx ​ FoliPlus D

Generic name: folic acid, vitamin d3
Dosage form: capsule, liquid filled

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

DermacinRx ​ FoliPlus D Description

FoliPlus D™ is an orally administered prescription folate product for the dietary management of patients with unique nutritional needs requiring increased folate levels and Vitamin D supplementation due to Vitamin D deficiency.

FoliPlus D™ should be administered under the supervision of a licensed medical practitioner.

Each softgel contains:

Folic Acid .....1 mg

Vitamin D 3 (cholecalciferol) .....3333 IU

Each softgel contains the following inactive ingredients: polyethylene glycol, gelatin, glycerin, corn oil, yellow 10 (ci 47005), titanium dioxide.

INDICATIONS AND DOSAGE

FoliPlus D™ is indicated for dietary management of patients with unique nutritional needs requiring increased folate levels and Vitamin D supplementation.

FoliPlus D can be taken by women of childbearing age, pregnant women, and lactating and nonlactating mothers.

DermacinRx ​ FoliPlus D - Clinical Pharmacology

The in vivo synthesis of the major biologically active metabolites of vitamin D occurs in two steps. The first hydroxylation of ergocalciferol takes place in the liver (to 25-hydroxyvitamin D) and the second in the kidneys (to 1,25-dihydroxyvitamin D). Vitamin D metabolites promote the active absorption of calcium and phosphorus by the small intestine, thus elevating serum calcium and phosphate levels sufficiently to permit bone mineralization. Vitamin D metabolites also mobilize calcium and phosphate from bone and probably increase the reabsorption of calcium and perhaps also of phosphate by the renal tubules.

There is a time lag of 10 to 24 hours between the administration of vitamin D and the initiation of its action in the body due to the necessity of synthesis of the active metabolites in the liver and kidneys. Parathyroid hormone is responsible for the regulation of this metabolism in the kidneys.

Contraindications

This product is contraindicated in patients with a known hypersensitivity to any of the ingredients. FoliPlus D is contraindicated in patients with hypercalcemia, malabsorption syndrome, abnorm