Diclegis

Generic name:doxylamine and pyridoxine [ dox-IL-a-meen-and-PIR-i-DOX-een ]
Drug class:Miscellaneous antiemetics

Medically reviewed by Sanjai Sinha, MD. Last updated on Jun 14, 2021.

What is Diclegis?

Diclegis is a delayed-release tablet containing a combination of doxylamine and pyridoxine. Doxylamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Pyridoxine is a form of vitamin B (B6).

Diclegis is used to treat nausea and vomiting during pregnancy, sometimes called morning sickness.

Diclegis may also be used for purposes not listed in this medication guide.

Warnings

Do not use Diclegis if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Before taking this medicine

Do not use Diclegis if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

You should not use this medicine if you are allergic to doxylamine or pyridoxine, or to other antihistamines such as Benadryl or Dramamine.