Generic name: diclofenac and misoprostol [ dye-KLOE-fen-ak-and-mye-so-PROST-ole ]
Brand name: Arthrotec
Dosage forms: oral delayed release tablet (50 mg-200 mcg; 75 mg-200 mcg); oral tablet (50 mg-200 mcg; 75 mg-200 mcg)
Drug class:Nonsteroidal anti-inflammatory drugs
What is diclofenac and misoprostol?
Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID). Misoprostol reduces stomach acid and replaces protective substances in the stomach that are reduced by NSAIDs.
Diclofenac and misoprostol is a combination medicine used to treat osteoarthritis and rheumatoid arthritis in people at high risk for developing stomach or intestinal ulcers.
Diclofenac and misoprostol may also be used for purposes not listed in this medication guide.
Warnings
Do not use if you are pregnant. Misoprostol can cause birth defects, miscarriage, premature labor, or rupture of the uterus. You must have a negative pregnancy test within 2 weeks before you start taking diclofenac and misoprostol. You may need to start taking diclofenac and misoprostol only on the 2nd or 3rd day of a normal menstrual period. Use effective birth control while you are using diclofenac and misoprostol.
Diclofenac can increase your risk of fatal heart attack or stroke. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Diclofenac may a...
