Diprolene AF
Generic name:betamethasone dipropionate
Dosage form: cream
Drug class:Topical steroids
Medically reviewed by Drugs.com. Last updated on Sep 1, 2021.
On This Page
- Indications and Usage
- Dosage and Administration
- Dosage Forms and Strengths
- Contraindications
- Warnings and Precautions
- Adverse Reactions/Side Effects
- Use In Specific Populations
- Description
- Clinical Pharmacology
- Nonclinical Toxicology
- Clinical Studies
- How Supplied/Storage and Handling
- Patient Counseling Information
Indications and Usage for Diprolene AF
DIPROLENE® AF Cream is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses in patients 13 years of age or older.
Diprolene AF Dosage and Administration
Apply a thin film of Diprolene AF Cream to the affected skin areas once or twice daily.
Therapy should be discontinued when control is achieved. Diprolene AF Cream is a high-potency corticosteroid. Treatment with Diprolene AF Cream should not exceed 50 g per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis [see Warnings and Precautions (5.1)].
Diprolene AF Cream should not be used with occlusive dressings unless directed by a physician.
Avoid contact with eyes. Wash hands after each application.
Avoid use on the face, groin, or axillae, or if skin atrophy is present at the treatment site.
Diprolene AF Cream is for topical use only. It is not for oral, ophthalmic, or intravaginal use.
Dosage Forms and Strengths
Cream, 0.05%. Each gram of Diprolene AF Cream, 0.05% contains 0.643 mg betamethasone dipropionate (equivalent to 0.5 mg betamethasone) in a white cream base.
Contraindications
Diprolene AF Cream is contraindicated in patients who are hypersensitive to betamethasone dipropionate, to other corticosteroids, or to any ingredient in this preparation.
Warnings and Precautions
Effects on Endocrine System
Diprolene AF Cream can produce reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency. This may occur during treatment or after withdrawal of treatment. Factors that predispose to HPA axis suppression include the use of high-potency steroids, large trea...