Diroximel fumarate
Generic name: diroximel fumarate [ dye-ROX-i-mel-FUE-ma-rate ]
Brand name: Vumerity
Dosage form: oral delayed release capsule (231 mg)
Drug class:Selective immunosuppressants
What is diroximel fumarate?
Diroximel fumarate is used to treat relapsing forms of multiple sclerosis in adults (including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease).
Diroximel fumarate may also be used for purposes not listed in this medication guide.
Warnings
You should not use diroximel fumarate if you have had a severe allergic reaction to diroximel fumarate, or if you also use dimethyl fumarate (Tecfidera).
Before taking this medicine
You should not use this medicine if:
you have had a severe allergic reaction to diroximel fumarate or dimethyl fumarate (Tecfidera); or
you also use dimethyl fumarate.
Tell your doctor if you have ever had:
kidney disease;
infections; or
low white blood cell (WBC) counts.
Tell your doctor if you are pregnant or breastfeeding.
Diroximel fumarate is not approved for use by anyone younger than 18 years old.
How should I take diroximel fumarate?
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using diroximel fumarate.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Swallow the capsule whole and do not crush, chew, break, or open it.
If you take diroximel fumarate with food, avoid foods that are high in calories or fat. Your meal or snack should not contain more than 700 calories or more than 30 grams of fat.
Do not drink alcohol when you take your diroximel fumarate dose.
Diroximel fumarate may cause flushing (a sudden sense of warmth or tingling), which should decrease over time. If this side effect is bothersome, ask your doctor about taking aspirin to help prevent flushing.
Store at room temperature away from moisture and heat.
Diroximel fumarate can have long lasting effects on your body. You may need frequent medical tests while using diroximel fumarate and for a short time after your last dose.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
