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Divalproex sodium
  • Treatments
  • Bipolar Disorder

Divalproex sodium

Generic name: divalproex sodium [ dye-val-PRO-ex ]
Brand names: Depakote, Depakote ER, Depakote Sprinkles
Dosage forms: oral delayed release capsule (125 mg); oral delayed release tablet (125 mg; 250 mg; 500 mg); oral tablet, extended release (250 mg; 500 mg)
Drug class:Fatty acid derivative anticonvulsants

Medically reviewed by Drugs.com on Feb 17, 2022. Written by Cerner Multum.

What is divalproex sodium?

Divalproex sodium comes in different pill forms that are for different uses.

Divalproex sodium tablets and capsules are used to treat seizures in people with epilepsy who are at least 10 years old. Divalproex sodium tablets are sometimes used together with other seizure medications.

Divalproex sodium tablets are also used in adults to prevent migraine headaches, or to treat manic episodes related to bipolar disorder (manic depression).

Divalproex sodium may also be used for purposes not listed in this medication guide.

Warnings

You should not use divalproex sodium if you have liver disease, a urea cycle disorder, or a genetic disorder such as Alpers' disease or Alpers-Huttenlocher syndrome.

Do not start or stop taking divalproex sodium during pregnancy without your doctor's advice. Divalproex sodium may harm an unborn baby, but having a seizure during pregnancy could harm both mother and baby. Do not use divalproex sodium to prevent migraine headaches if you are pregnant.

Divalproex sodium can cause liver failure that may be fatal, especially in children under age 2 and in people with liver pro...