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Dofetilide
  • Treatments
  • Arrhythmia

Dofetilide

Generic name: dofetilide [ doe-FET-i-lide ]
Brand name: Tikosyn
Dosage form: oral capsule (125 mcg; 250 mcg; 500 mcg)
Drug class:Group III antiarrhythmics

Medically reviewed by Drugs.com on Apr 4, 2022. Written by Cerner Multum.

What is dofetilide?

Dofetilide is a heart rhythm medicine, also called an antiarrhythmic.

Dofetilide is used to help keep the heart beating normally in people with certain heart rhythm disorders of the atrium (the upper chambers of the heart that allow blood to flow into the heart). Dofetilide is used in people with atrial fibrillation or atrial flutter.

Dofetilide may also be used for purposes not listed in this medication guide.

Warnings

You should not take dofetilide if you have severe kidney disease or a history of Long QT syndrome.

Serious drug interactions can occur when certain medicines are used together with dofetilide. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.

You will need to spend at least 3 days in a hospital setting when you first start taking dofetilide. This is so your heart rhythm and kidney function can be monitored in case the medicine causes serious side effects.

Before taking this medicine

You should not take dofetilide if you are allergic to it, or if you have:

  • severe kidney disease (or if you are on dialysis); or

  • a history of Long QT syndrome.

Some medicines can cause unwanted or dangerous effects when used with dofetilide, and should not be used at the same time. Your doctor may need to change your treatment plan ...