Dolutegravir
Generic name: dolutegravir [ DOE-loo-TEG-ra-vir ]
Brand names: Tivicay, Tivicay PD
Dosage forms: oral tablet (10 mg; 25 mg; 50 mg); oral tablet, dispersible (5 mg)
Drug class:Integrase strand transfer inhibitor
What is dolutegravir?
Dolutegravir is an antiviral medicine that is used with other medications to treat HIV, the virus that can cause the acquired immunodeficiency syndrome (AIDS). Dolutegravir is not a cure for HIV or AIDS.
Dolutegravir is for use in adults and children as young as 4 weeks old and weighing at least 6 pounds (3 kilograms).
Dolutegravir may also be used for purposes not listed in this medication guide.
Warnings
You should not use dolutegravir if you are also taking dofetilide (Tikosyn).
Taking dolutegravir during the first trimester of pregnancy may cause birth defects. Use effective birth control to prevent pregnancy while you are using dolutegravir.
Before taking this medicine
You should not use dolutegravir if you are allergic to it, or if you are also taking dofetilide (Tikosyn).
Tell your doctor if you have ever had:
liver disease, especially hepatitis B or C.
You may need to have a negative pregnancy test before starting this treatment.
Dolutegravir may harm an unborn baby if you take the medicine at the time of conception or during the first 12 weeks of pregnancy. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.
HIV can be passed to your baby if the virus is not controlled during pregnancy. If you are pregnant, your name may be listed on a registry to track any effects of antiviral medicine on the baby. Use your medications properly to control HIV.
Women with HIV or AIDS should not breastfeed. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.
How should I take dolutegravir?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
You may take dolutegravir with or without food.
Do not crush or chew a dispersible tablet whole. Swallow the tablet whole, or place it in a small amount of water. Allow the tablet to disperse (it will not dissolve completely). Stir and give the mixture to the child right away. The amount of water needed will depend on the number of tablets needed for your child's dose. Follow the instructions provided with your medicine.
The dolutegravir regular tablet an...
