Dolutegravir and lamivudine
Generic name: dolutegravir and lamivudine [ DOE-loo-TEG-ra-vir-and-la-MIV-ue-deen ]
Brand name: Dovato
Dosage form: oral tablet (50 mg-300 mg)
Drug class:Antiviral combinations
What is dolutegravir and lamivudine?
Dolutegravir and lamivudine is a combination antiviral medicine used to treat human immunodeficiency virus (HIV), the virus that can cause the acquired immunodeficiency syndrome (AIDS). dolutegravir and lamivudine is not a cure for HIV or AIDS.
Dolutegravir and lamivudine is sometimes used in adults who have never been treated with other HIV medications.
Dolutegravir and lamivudine is also used to replace other HIV medications in adults with suppressed viral loads. Your doctor will determine which medication is best for you.
Dolutegravir and lamivudine may also be used for purposes not listed in this medication guide.
Warnings
You should not use this medicine if you are also taking dofetilide (Tikosyn).
Taking dolutegravir and lamivudine during the first trimester of pregnancy may cause birth defects. Use effective birth control to prevent pregnancy while you are using this medicine.
If you've ever had hepatitis B, it may become active and resistant to medication while you are taking dolutegravir and lamivudine. Hepatitis B may also get worse after you stop using this medicine. You may need frequent liver function tests for several months.
Before taking this medicine
You should not use dolutegravir and lamivudine if you are allergic to dolutegravir or lamivudine, or if you are also taking dofetilide (Tikosyn).
Tell your doctor if you have ever had:
kidney problems; or
liver disease, especially hepatitis B or C.
You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, if you are overweight, or if you are a woman. Ask your doctor about your risk.
You may need to have a negative pregnancy test before starting this treatment.
Dolutegravir and lamivudine may harm an unborn baby if you take the medicine at the time of conception or during the first 12 weeks of pregnancy. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.
Tell your doctor if you are pregnant, and use your medications properly to control your infection. HIV can b...
