Duavee
Generic name:bazedoxifene and conjugated estrogens [ BA-ze-DOX-i-feen-and-KON-joo-GAY-ted-ES-troe-jens ]
Drug class:Sex hormone combinations
What is Duavee?
Duavee contains a combination of bazedoxifene and conjugated estrogens. Bazedoxifene blocks estrogen from reaching certain cells in the uterine lining, to protect against overgrowth of uterine tissue.
Estrogen is a female sex hormone produced by the ovaries. Conjugated strogens are a mixture of estrogen hormones.
Duavee is used short-term in women after menopause to treat moderate to severe hot flashes, and to prevent osteoporosis.
Duavee is used in women who have NOT had a hysterectomy (uterus removed).
Warnings
You should not use Duavee if you have: undiagnosed vaginal bleeding, liver disease, a bleeding disorder, if you will have major surgery, or if you have ever had a heart attack, a stroke, a blood clot, or cancer of the breast, uterus/cervix, or vagina.
Using Duavee can increase your risk of blood clots, stroke, or heart attack, or cancer of the breast, uterus, or ovaries. Estrogens should not be used to prevent heart disease, stroke, or dementia.
Estrogens may increase your risk of developing a condition that may lead to uterine cancer. Report any unusual vaginal bleeding right away.
Duavee is for short-term use at the lowest dose needed to treat your condition.
Do not take any other estrogens while you are taking this medicine.
Before taking this medicine
You should not use Duavee if you are allergic to bazedoxifene or conjugated estrogens, or if you have:
unusual vaginal bleeding that has not been checked by a doctor;
liver disease;
a history of heart attack, stroke, or blood clot;
an increased risk of having blood clots due to a heart problem or a hereditary blood disorder; or
a history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina.
Do not use other estrogen products while you are taking Duavee.
Using this medicine can increase your risk of blood clots, stroke, or heart attack. You are even more at risk if you have high blood pressure, diabetes, high cholesterol, if you are overweight, or if you smoke.
Duavee should not be used to prevent heart disease, stroke, or dementia, because...
