Durvalumab
Generic name: durvalumab [ dur-VAL-ue-mab ]
Brand name: Imfinzi
Dosage form: intravenous solution (50 mg/mL)
Drug class:Anti-PD-1 monoclonal antibodies
What is durvalumab?
Durvalumab is used to treat cancer of the lungs, bladder, or urinary tract.
Durvalumab is sometimes given when the cancer has spread to other parts of the body or cannot be removed with surgery, or when other treatments did not work or have stopped working.
Durvalumab may also be used for purposes not listed in this medication guide.
Warnings
Durvalumab may cause serious or life-threatening side effects on your lungs, liver, pancreas, kidneys, intestines, thyroid, pituitary, or adrenal glands.
Call your doctor at once if you have new or unusual symptoms, such as: tiredness, mood changes, headaches, vision problems, muscle weakness, stomach problems, weight changes, skin rash, hair loss, bleeding or bruising, yellowing of your skin or eyes, increased or decreased urination, dark urine, bloody or tarry stools, worsening cough, chest pain, or trouble breathing.
Before taking this medicine
Tell your doctor if you have an active infection, or if you have ever had:
an organ transplant or stem cell transplant (recent or planned);
lung disease or breathing problems;
radiation treatment of your chest area; or
an autoimmune disorder such as lupus, ulcerative colitis, or Crohn's disease.
Durvalumab may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using durvalumab and for at least 3 months after your last dose. Tell your doctor if you become pregnant.
Do not breastfeed while using durvalumab, and for at least 3 months after your last dose.
How is durvalumab given?
Durvalumab is given as an infusion into a vein, usually once every 2, 3 or 4 weeks. A healthcare provider will give you this injection.
This medicine must be given slowly and the infusion can take about 1 hour to complete.
You may need frequent medical tests.
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your durvalumab injection.
What happens if I overdose?
Since durvalumab is given by a healthcare professional in a medical setting, an overdose is unlikely to ...
