Empaveli

Generic name:pegcetacoplan
Dosage form: injection, for subcutaneous use
Drug class:Selective immunosuppressants

Medically reviewed by Judith Stewart, BPharm. Last updated on Sep 1, 2021.

What is Empaveli?

Empaveli is a prescription medicine used to treat adults with a disease called paroxysmal nocturnal hemoglobinuria (PNH).

It is not known if Empaveli is safe and effective in children.

Important information

Empaveli is a medicine that can affect your immune system. Empaveli can lower the ability of your immune system to fight infections.

• Empaveli may increase your chance of getting serious and life-threatening meningococcal infections.
• Meningococcal infections may quickly become life-threatening and cause death if not recognized and treated early.
• Empaveli may also increase the risk of getting serious infections. People who take Empaveli may have an increased risk of getting infections caused by Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae type B. Serious infections may quickly become life threatening and cause death if not recognized and treated early.
• You must be vaccinated against these bacteria at least 2 weeks before your first dose if you have not already had these vaccines.
• If your healthcare provider decides that urgent treatment with Empaveli is needed, you should receive the required vaccinations as soon as possible.
• If you have not been vaccinated and Empaveli therapy must be initiated immediately, you should also receive 2 weeks of antibiotics with your vaccinations.
• If you have been vaccinated against these bacteria in the past, you might need additional vaccinations before starting treatment. Your healthcare provider will decide if you need additional vaccinations.
• Vaccines reduce the risk of serious infections, but do not prevent all serious infections. Call your healthcare provider or get emergency medi..