Enasidenib
Generic name: enasidenib [ EN-a-SID-a-nib ]
Brand name: Idhifa
Dosage form: oral tablet (100 mg; 50 mg)
Drug class:Miscellaneous antineoplastics
What is enasidenib?
Enasidenib is used to treat acute myeloid leukemia (AML) in adults with an IDH2 mutation. enasidenib is used when AML has come back or has not improved with prior treatment.
Enasidenib may also be used for purposes not listed in this medication guide.
Warnings
Seek medical help right away if you have symptoms of differentiation syndrome within 10 days to 5 months after taking enasidenib. Symptoms include fever, cough, trouble breathing, bone pain, rapid weight gain, or swelling in your arms, legs, underarms, groin, or neck.
Before taking this medicine
You may need to have a negative pregnancy test before starting this treatment.
Both men and women using enasidenib should use birth control to prevent pregnancy. Enasidenib can harm an unborn baby if the mother or father is using this medicine.
Keep using birth control for at least 2 months after your last dose. Tell your doctor right away if a pregnancy occurs.
Do not breastfeed while using this medicine, and for at least 2 months after your last dose.
How should I take enasidenib?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Drink plenty of liquids while you are taking enasidenib.
Take with or without food, at the same time each day
Do not crush, chew, or break an enasidenib tablet. Swallow it whole.
If you vomit shortly after taking enasidenib, do not take another dose. Take your next dose as scheduled.
You may need frequent medical tests and your cancer treatments may be delayed based on the results.
Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with the canister of moisture-absorbing preservative.
What happens if I miss a dose?
Take the missed dose on the same day you remember it. Take your next dose at the regular time and stay on your once-daily schedule. Do not use 2 doses in one day.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking enasidenib?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Enasidenib side effects
Get emergency medical help if you have signs of an allergic reaction:
