Encorafenib
Generic name: encorafenib [ EN-koe-RAF-e-nib ]
Brand name: Braftovi
Dosage form: oral capsule (75 mg)
Drug class:Multikinase inhibitors
What is encorafenib?
Encorafenib is used in combination with a medicine called binimetinib (Mektovi) to treat melanoma (skin cancer) that cannot be treated with surgery or has spread to other parts of the body.
Encorafenib is used in combination with a medicine called cetuximab (Erbitux) to treat colorectal cancer that has spread to other parts of the body.
Encorafenib is used only if your cancer has a specific genetic marker (an abnormal "BRAF" gene). Your doctor will test you for this gene. encorafenib is not for treating wild-type BRAF cancers.
Encorafenib may also be used for purposes not listed in this medication guide.
Warnings
Encorafenib can harm an unborn baby. Do not use if you are pregnant. Use a non-hormonal form of birth control to prevent pregnancy while using encorafenib and for at least 2 weeks after your last dose.
Although this medicine is used to treat melanoma, using encorafenib may increase your risk of developing other types of skin cancer. Ask your doctor about your specific risk. Tell your doctor if you notice any new skin symptoms.
Before taking this medicine
You should not use encorafenib if you are allergic to it.
Tell your doctor if you have ever had:
heart problems;
long QT syndrome (in you or a family member);
lung disease;
liver or kidney disease;
eye problems (especially a problem with your retina); or
bleeding problems, or a blood clot.
Although encorafenib is used to treat melanoma, using encorafenib may increase your risk of developing other types of skin cancer. Tell your doctor if you notice any new skin symptoms such as redness, warts, sores that will not heal, or a mole that has changed in size or color.
You may need to have a negative pregnancy test before starting this treatment.
Do not use encorafenib if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 2 weeks after your last dose. Tell your doctor if you become pregnant.
Encorafenib can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vagin...
