Equioxx Injection

Generic name: firocoxib injection, solution
Dosage form: FOR ANIMAL USE ONLY

Non-steroidal anti-inflammatory drug for intravenous use in horses only.

CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Description

EQUIOXX (firocoxib) belongs to the coxib class of non-narcotic, non-steroidal anti-inflammatory drugs (NSAID). Firocoxib is a white crystalline compound described chemically as 3-(cyclopropylmethoxy)-4-(4-(methylsulfonyl)phenyl)-5, 5-dimethylfuranone. The empirical formula is C17H20O5S, and the molecular weight is 336.4. The structural formula is shown below:

Equioxx Injection is a colorless to pale yellow solution. Each mL of Equioxx Injection for Horses contains 20 mg of firocoxib as a free base, 550 mg of polyethylene glycol (PEG 400) and 600 mg of glycerol formal.

Indications

Equioxx Injection is administered for up to 5 days for the control of pain and inflammation associated with osteoarthritis in horses.

Dosage and Administration

Always provide the Client Information Sheet with the prescription. The recommended dosage of Equioxx Injection for intravenous administration in horses is 0.04 mg/lb (0.09 mg/kg) of body weight once daily for up to 5 days. If further treatment is needed, EQUIOXX (firocoxib) Oral Paste for horses can be used at a dosage of 0.045 mg/lb (0.1 mg/kg) body weight for up to an additional 9 days of treatment. The overall duration of treatment with Equioxx Injection and EQUIOXX Oral Paste will be dependent on the response observed, but should not exceed 14 days. See EQUIOXX Oral Paste for horses package insert for dosage and administration. Equioxx Injection is a non-aqueous solution, and therefore should not be added to an aqueous solution (such as intravenous infusion lines).

Contraindications

Horses with hypersensitivity to firocoxib should not receive Equioxx Injection.

Warnings

For intravenous use in horses only. Do not use in horses intended for human consumption.

Human Warnings

Not for use in humans. Keep this and all medications out of the reach of children. Consult a physician in case of accidental human exposure.

Animal Safety

Clients should be advised to observe for signs of potential drug toxicity and be give a Client Information Sheet with each prescription.

For technical assistance or to report suspected adverse events, call 1-877-217-3543.