Ergomar Sublingual Tablets
Generic name:ergotamine tartrate
Dosage form: tablet ,sublingual
Drug class:Antimigraine agents
Medically reviewed by Drugs.com. Last updated on Sep 1, 2020.
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(Ergotamine Tartrate Sublingual Tablets, USP)
Rx Only
Serious and/or life-threatening peripheral ischemia has been associated with the coadministration of ergotamine tartrate with potent CYP 3A4 inhibitors including protease inhibitors and macrolide antibiotics. Because CYP 3A4 inhibition elevates the serum levels of ergotamine tartrate, the risk for vasospasm leading to cerebral ischemia and/or ischemia of the extremities is increased. Hence, concomitant use of these medications is contraindicated. (See also CONTRAINDICATIONS and WARNINGS section)
DESCRIPTION:
Ergomar® Sublingual Tablets
| Ergotamine Tartrate Sublingual Tablets USP ... 2 mg |
Inactive Ingredients: Microcrystalline Cellulose NF, Natural Peppermint Flavor Powder, Crospovidone NF, Saccharin Sodium USP Powder, D&C Yellow #10 Lake, Magnesium Stearate NF, FD&C Blue #1 Aluminum Lake.
CLINICAL PHARMACOLOGY:
Ergotamine is an alpha adrenergic blocking agent with a direct stimulating effect on the smooth muscle of peripheral and cranial blood vessels and produces depression of central vasomotor centers. The compound also has the properties of serotonin antagonism. In comparison to hydrogenated ergotamine, the adrenergic blocking actions are less pronounced and vasoconstrictive actions are greater.
Pharmacokinetics: Interactions
Pharmac...
