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Ertugliflozin and metformin
  • Treatments
  • Diabetes
  • Type 2

Ertugliflozin and metformin

Generic name: ertugliflozin and metformin [ ER-too-gli-FLOE-zin-and-met-FOR-min ]
Brand name: Segluromet
Dosage form: oral tablet (2.5 mg-1000 mg; 2.5 mg-500 mg; 7.5 mg-1000 mg; 7.5 mg-500 mg)
Drug class:Antidiabetic combinations

Medically reviewed by Drugs.com on Mar 21, 2022. Written by Cerner Multum.

What is ertugliflozin and metformin?

Ertugliflozin and metformin is a combination medicine used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. ertugliflozin and metformin is not for treating type 1 diabetes.

Ertugliflozin and metformin may also be used for purposes not listed in this medication guide.

Warnings

You should not use this medicine if you have severe kidney disease, if you are on dialysis, or if you have diabetic ketoacidosis.

Ertugliflozin may increase your risk of lower leg amputation, especially if you have had a prior amputation, a foot ulcer, heart disease, circulation problems, or nerve damage.

Ertugliflozin can cause serious infections in the penis or vagina. Get medical help right away if you have burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, or if you don't feel well.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.

Before taking this medicine

You should not use ertugliflozin and metformin if you are allergic to ertugliflozin or metformin, or if you have:

  • severe kidney disease (or if you are on dialysis); or

  • diabetic ketoacidosis (call your doctor for treatment).

If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking ertugliflozin and metformin.

Ertugliflozin may increase your risk of lower leg amputation, especially if you have had a prior amputation, a foot ulcer, heart disease, circulation problems, or nerve damage.

Tell your doctor if you have ever had:

  • heart problems;

  • a diabetic foot ulcer or amputation;

  • circulation problems or nerve problems in your legs or feet;

  • liver or kidney disease;

  • high ketone levels in your blood or urine;

  • bladder infections or other urination problems;