Erythrocin Injection USP

Generic name:erythrocin lactobionate
Dosage form: injection, powder, lyophilized, for solution
Drug class:Macrolides

Medically reviewed by Drugs.com. Last updated on Feb 21, 2022.

Single-doseADD-VantageTM Vials Rx only
For Intravenous Use Only

To reduce the development of drug-resistant bacteria and maintain the effectiveness of erythromycin and other antibacterial drugs, erythromycin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

Erythrocin Injection USP Description

ErythrocinTM Lactobionate-IV (erythromycin lactobionate for injection, USP) is a lyophilized powder for intravenous infusion only. It is prepared as a solution and lyophilized in its final container. The Erythrocin Lactobionate-IV ADD-VantageTM vial is designed for use only with the ADD-Vantage flexible diluent container. After appropriate dilution, the Erythrocin Lactobionate-IV ADD-Vantage Delivery System contains erythromycin lactobionate equivalent to either 500 mg of erythromycin activity in 100 mL.

The solutions contain no bacteriostat, antimicrobial agent (except erythromycin) or buffer and are intended for use as a single-dose injection only with the ADD-Vantage flexible diluent container.

Erythromycin is produced by a strain of Streptomyces erythraeus and belongs to the macrolide group of antibiotics. It is basic and readily forms salts with acids. Erythromycin lactobionate has the following structure:

Erythrocin Injection USP - Clinical Pharmacology

Erythromycin diffuses readily into most body fluids. In the absence of meningeal inflammation, low concentrations are normally achieved in the spinal fluid but the passage of the drug across the blood-brain barrier increases in meningitis. Erythromycin crosses ...