Erythromycin and benzoyl peroxide (Topical)

Medically reviewed by Drugs.com. Last updated on Jun 2, 2022.

Commonly used brand name(s)

In the U.S.

• Benzamycin Pak

Available Dosage Forms:

• Gel/Jelly

Therapeutic Class: Antiacne

Chemical Class: Macrolide

Uses for erythromycin and benzoyl peroxide

Erythromycin and benzoyl peroxide combination is used to treat acne. It works by killing the bacteria that cause acne and by keeping the skin pores clean (tiny openings on the skin).

Erythromycin and benzoyl peroxide is available only with your doctor's prescription.

Before using erythromycin and benzoyl peroxide

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For erythromycin and benzoyl peroxide, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to erythromycin and benzoyl peroxide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of erythromycin and benzoyl peroxide combination in children younger than 12 years of age. Safety and efficacy have not been established.

Geriatric

No information is available on the relationship of age to the effects of erythromycin and benzoyl peroxide combination in geriatric patients.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking erythromycin and benzoyl peroxide, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using erythromycin and benzoyl peroxide with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Astemizole
• Bepridil
• Cisapride
• Colchicine
• Dihydroergotamine
• Dronedarone
• Eliglustat
• Ergoloid Mesylates
• Ergonovine
• Ergotamine
• Flibanserin
• Fluconazole
• Grepafloxacin
• Levoketoconazole
• Levomethadyl
• Lomitapide
• Lovastatin
• Mesoridazine
• Methylergonovine
• Methysergide
• Pimozide
• Piperaquine
• Posaconazole
• Saquinavir
• Simvastatin
• Sparfloxacin
• Terfenadine
• Thioridazine
• Ziprasidone

Using erythromycin and benzoyl peroxide with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Abametapir
• Acalabrutinib
• Acecainide
• Afatinib
• Ajm...