Evinacumab

Generic name: evinacumab [ E-vin-AK-ue-mab ]
Brand name: Evkeeza
Dosage form: intravenous solution (150 mg/mL)
Drug class:Miscellaneous antihyperlipidemic agents

Medically reviewed by Drugs.com on Mar 11, 2021. Written by Cerner Multum.

What is evinacumab?

Evinacumab is used with other medications to lower cholesterol in adults and children at least 12 years old who have an inherited type of high cholesterol.

Evinacumab is not for use in treating high cholesterol that is caused by diet or other factors.

Evinacumab may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not be treated with evinacumab if you are allergic to it.

You may need to have a negative pregnancy test before starting this treatment.

Evinacumab may harm an unborn baby. Use effective birth control to prevent pregnancy while using evinacumab, and for at least 5 months after your last dose. Tell your doctor if you become pregnant.

It may not be safe to breastfeed while using evinacumab. Ask your doctor about any risk.

Evinacumab is not approved for use by anyone younger than 12 years old.

How is evinacumab given?

Evinacumab is given as an infusion into a vein, usually once per month. A healthcare provider will give you this injection.

This medicine must be given slowly, and the infusion can take about 60 minutes to complete.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your evinacumab injection.

What happens if I overdose?

Since evinacumab is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving evinacumab?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Evinacumab side effects

Get emergency medical help if you have signs of an allergic reaction:hives, rash, itching; feeling light-headed; wheezing, difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your caregiver if you feel nauseated, itchy, feverish, or have a stuffy nose or muscle weakness.

Your evinacumab treatments may be delayed or permanently discontinued if you have certain side effects.

Common side effects of...