Alfentanil
Generic name: Alfentanil hydrochloride
Dosage form: injection, solution
Drug class:Narcotic analgesics
Medically reviewed by Drugs.com. Last updated on Oct 1, 2020.
On This Page
- Boxed Warning
- Indications and Usage
- Dosage and Administration
- Dosage Forms and Strengths
- Contraindications
- Warnings and Precautions
- Adverse Reactions/Side Effects
- Drug Interactions
- Use In Specific Populations
- Drug Abuse and Dependence
- Overdosage
- Description
- Clinical Pharmacology
- Nonclinical Toxicology
- How Supplied/Storage and Handling
Addiction, Abuse, and Misuse
Alfentanil HCl injection exposes patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. Assess each patient's risk prior to prescribing Alfentanil HCl Injection, and monitor all patients regularly for the development of these behaviors and conditions[see Warnings and Precautions (5.1)].
Indications and Usage for Alfentanil
Alfentanil HCl Injection is indicated:
- as an analgesic adjunct given in incremental doses in the maintenance of anesthesia with barbiturate/nitrous oxide/oxygen.
- as an analgesic administered by continuous infusion with nitrous oxide/oxygen in the maintenance of general anesthesia.
- as a primary anesthetic agent for the induction of anesthesia in patients undergoing general surgery in which endotracheal intubation and mechanical ventilation are required.
- as the analgesic component for monitored anesthesia care (MAC).
Alfentanil Dosage and Administration
Important Dosage and Administration Instructions
Alfentanil HCl Injection should be administered only by persons specifically trained in the use of intravenous anesthetics and management of the respiratory effects of potent opioids.
In patients administered high doses of Alfentanil HCl Injection, it is essential that qualified personnel and adequate facilities are available for the management of postoperative respiratory depression.
- Ensure that an opioid antagonist, resuscitative and intubation equipment, and oxygen are readily available.
- Individualize dosage based on factors such as age, body weight, ...