Factor XIII
Generic name: factor XIII [ FAK-tor-13 ]
Brand names: Corifact, Tretten
Dosage form: intravenous powder for injection (-; recombinant A-subunit)
Drug class:Miscellaneous coagulation modifiers
What is factor XIII?
Factor XIII (thirteen) is a naturally occurring protein in the blood that helps blood to clot. A lack of clotting factors can cause uncontrolled bleeding, as the blood is unable to clot properly. factor XIII works by temporarily raising levels of these factor XIII in the blood to aid in clotting.
Factor XIII is used to prevent bleeding episodes in people with a hereditary bleeding disorder caused by a deficiency of Factor XIII.
Factor XIII will not treat a bleeding episode that has already begun.
Factor XIII may also be used for purposes not listed in this medication guide.
Warnings
You should not use this medicine if you are allergic to any medicine made with human plasma.
Before taking this medicine
You should not use factor XIII if you are allergic to factor XIII or to any medicine made with human plasma.
To make sure factor XIII is safe for you, tell your doctor if you have:
It is not known whether factor XIII will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
It is not known whether factor XIII passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Factor XIII is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.
How should I take factor XIII?
Factor XIII is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.
Factor XIII is usually given once every 4 weeks. Follow your doctor's dosing instructions very carefully.
Factor XIII is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medicine.
Allow the mixture to reach room temperature before giving the injection. Do not heat the medicine before using.
Factor XIII should look clear or slightly yellow in color. Do not use the medication if it has changed colors or has particles in it. Call your doctor for a new prescription.
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