Alirocumab
Generic name: alirocumab [ AL-i-ROK-ue-mab ]
Brand names: Praluent Pen, Praluent Syringe
Dosage form: subcutaneous solution (150 mg/mL; 75 mg/mL)
Drug class:PCSK9 inhibitors
What is alirocumab?
Alirocumab is a human monoclonal antibody. It works by helping the liver reduce levels of "bad" cholesterol (low-density lipoprotein, or LDL) circulating in your blood.
Alirocumab is used in adults with heart disease to lower the risk of heart attack, stroke, and certain types of chest pain conditions (unstable angina) requiring hospitalization.
Alirocumab is also used together with a low-fat diet, alone or together with other cholesterol-lowering medications ("statin" medicines) in adults with high blood cholesterol levels called primary hyperlipidemia (including a type of high cholesterol called heterozygous familial hypercholesterolemia), an inherited type of high cholesterol. This condition can cause high blood levels of LDL cholesterol, and can also cause plaque to build up inside your arteries.
Alirocumab is also used along with other LDL-lowering treatments in adults with a type of high cholesterol called homozygous familial hypercholesterolemia, who need additional lowering of LDL-C.
Warnings
Use alirocumab only as directed. Tell your doctor if you use other medicines, including prescription and over-the-counter medicines, vitamins, and herbal supplements, or have other medical conditions or allergies.
Before taking this medicine
You should not use alirocumab if you are allergic to it.
Not approved for use by anyone younger than 18 years old.
It is not known if alirocumab will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of alirocumab on the baby.
Do not breastfeed.
How should I use alirocumab?
Take alirocumab exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.
Alirocumab is injected under the skin, usually once every 2 to 4 weeks. It may take up to 20 seconds to inject each dose.
Ask your doctor or pharmacist if you don't understand how to use an injection.
Do not shake alirocumab. Prepare an injection only when you are ready to give it. Call your pharmacist if the medicine looks cloudy, has changed colors, or has particles in it.
Do not reuse a needle or syringe. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.
Throw away an injection pen after one use, even if there is still medicine l...
