Ferumoxytol Injection
Dosage form: injection
Drug class:Iron products
Medically reviewed by Drugs.com. Last updated on Sep 1, 2020.
On This Page
- Boxed Warning
- Indications and Usage
- Dosage and Administration
- Dosage Forms and Strengths
- Contraindications
- Warnings and Precautions
- Adverse Reactions/Side Effects
- Drug Interactions
- Use In Specific Populations
- Overdosage
- Description
- Clinical Pharmacology
- Nonclinical Toxicology
- Clinical Studies
- Patient Counseling Information
WARNING: RISK FOR SERIOUS HYPERSENSITIVITY/ANAPHYLAXIS REACTIONS
Fatal and serious hypersensitivity reactions including anaphylaxis have occurred in patients receiving ferumoxytol. Initial symptoms may include hypotension, syncope, unresponsiveness, cardiac/cardiorespiratory arrest.
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- Only administer ferumoxytol as an intravenous infusion over at least 15 minutes and only when personnel and therapies are immediately available for the treatment of anaphylaxis and other hypersensitivity reactions[see Warnings and Precautions (5.1)].
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- Observe for signs or symptoms of hypersensitivity reactions during and for at least 30 minutes following ferumoxytol infusion including monitoring of blood pressure and pulse during and after ferumoxytol administration[see Warnings and Precautions (5.1)].
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- Hypersensitivity reactions have occurred in patients in whom a previous ferumoxytol dose was tolerated[see Warnings and Precautions (5.1)].
Indications and Usage for Ferumoxytol Injection
Ferumoxytol is indicated for the treatment of iron deficiency anemia (IDA) in adult patients:
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- who have intolerance to oral iron or have had unsatisfactory response to oral iron or
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- who have chronic kidney disease (CKD).
Ferumoxytol Injection Dosage and Administration
The recommended dose of Ferumoxytol Injection is an initial 510 mg dose followed b...
