Fibrinogen and thrombin, human (Topical application)

Medically reviewed by Drugs.com. Last updated on Mar 26, 2022.

Commonly used brand name(s)

In the U.S.

Evarrest
Raplixa
Tachosil

Available Dosage Forms:

Solution
Sheet

Therapeutic Class: Fibrin Sealant

Uses for fibrinogen and thrombin, human

Fibrinogen and thrombin human topical powder or patch is used to help control bleeding during surgery when other procedures to close a wound or incision, such as stitches, bands, and heat cannot be used. Fibrinogen and thrombin, human is a fibrin sealant.

Fibrinogen and thrombin, human contains man-made proteins (fibrinogen and thrombin) that are used to stop bleeding by helping the blood to clot.

Fibrinogen and thrombin, human is to be given only by or under the supervision of your doctor.

Before using fibrinogen and thrombin, human

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For fibrinogen and thrombin, human, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to fibrinogen and thrombin, human or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of fibrinogen and thrombin human topical powder or patch in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of fibrinogen and thrombin human topical powder or patch in the elderly.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Fibrinogen and thrombin, human Topical application