FreAmine HBC

Generic name:isoleucine, leucine, lysine acetate, methionine, phenylalanine, threonine, tryptophan, valine, alanine, arginine, histidine, proline, serine, glycine and cysteine hydrochloride
Dosage form: injection, solution
Drug class:Intravenous nutritional products

Medically reviewed by Drugs.com. Last updated on Oct 22, 2021.

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FreAmine HBC Description

6.9% FreAmine HBC® (Amino Acid Injection) is a sterile, nonpyrogenic, hypertonic solution containing crystalline amino acids. A 750 mL partial fill unit provides a total of 7.3 g of nitrogen in 50 g of amino acids equal to 46 grams of protein equivalent. All amino acids designated USP are the "L"- isomer with the exception of Glycine USP, which does not have an isomer.

Each 100 mL contains:

Essential Amino Acids

Isoleucine USP ..... 0.76 g

Leucine USP ..... 1.37 g

Lysine ..... 0.41 g

(added as Lysine Acetate USP ..... 0.58 g)

Methionine USP ..... 0.25 g

Phenylalanine USP ..... 0.32 g

Threonine USP ..... 0.20 g

Tryptophan USP ..... 0.09 g

Valine USP ..... 0.88 g

Nonessential Amino Acids

Alanine USP ..... 0.40 g

Arginine USP ..... 0.58 g

Histidine USP ..... 0.16 g

Proline USP ..... 0.63 g

Serine USP ..... 0.33 g

Glycine USP ..... 0.33 g

Cysteine ..... <0.014 g

(as Cysteine HCl•H2O USP ..... <0.020 g)

Sodium Bisulfite (as an antioxidant) ..... <0.10 g

Water for Injection USP ..... qs

pH adjusted with Glacial Acetic Acid USP

pH: 6.5 (6.0 – 7.0)

Calculated Osmolarity: 620 mOsmol/liter

Concentration of Electrolytes (mEq/liter): Sodium 10; Chloride <3 Acetate Approx. 59.3 (provided as acetic acid and lysine acetate)

FreAmine HBC - Clinical Pharmacology

6.9% FreAmine HBC® solution provides a mixture of biologically utilizable essential and nonessential crystalline amino acids in concentrated form for protein synthesis. 6.9% FreAmine HBC® contains a high concentration of ...