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Gimoti
  • Treatments
  • Gastroparesis

Gimoti

Generic name:metoclopramide (nasal spray)
Drug class:GI stimulants

Medically reviewed by Judith Stewart, BPharm. Last updated on Jul 30, 2020.

What is Gimoti?

  • Gimoti is a prescription medicine used in adults to relieve the symptoms of slow stomach emptying in people with diabetes.
  • Gimoti is not recommended for use in people who:
    • have kidney or liver problems.
    • have been told that an enzyme in their body, called CYP2D6, breaks down (metabolizes) certain medicines in the body too slowly.
    • are also taking medicine called CYP2D6 inhibitors, which slows how fast the body breaks down (metabolizes) certain medicines.
  • Gimoti is not recommended for use in children.
  • It is not known if this medicine is safe and effective in children.

Warnings

Gimoti can cause serious side effects, including:
Tardive dyskinesia (abnormal muscle movements). These movements happen mostly in the face muscles. You cannot control these movements. They may not go away even after stopping Gimoti.
Your chances for getting tardive dyskinesia increase:

  • the longer you take Gimoti and the more Gimoti you take. You should not take Gimoti for more than 8 weeks at a time, and you should not take products containing metoclopramide (including Gimoti) for more than 12 weeks at a time.
  • if you are older, especially if you are an older woman.
  • because you have diabetes.

It is not possible for your healthcare provider to know if you will get tardive dyskinesia if you take Gimoti.
Call your healthcare provider right away if you get movements you cannot stop or control, such as:

  • lip smacking, chewing, or puckering up your mouth
  • frowning or scowling
  • sticking out your tongue
  • blinking and moving your eyes
  • shaking of your arms and legs

Your healthcare provider may stop treatment if you develop signs or symptoms of tardive dyskinesia.
See the section Gimoti side effects